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Ten years ago, a seminal paper published by Cytel Founder Cyrus Mehta, introduced the Promising Zone Design to..

ACDM’s (Association for Clinical Data Management) eDigital data management expert group (DMEG) focuses on driving..

Over the past decade, single arm trials have emerged as an accepted way of assessing a new treatment intervention...

When selecting clinical trial designs, how many design options should a sponsor explore? Would a sponsor feel more..

Bayesian methods have been playing a key role in transforming clinical research in therapeutic areas such as oncology..

Bayesian methods allow for the incorporation of prior knowledge, in terms of either expert opinion from clinicians or..

For many decades the Pareto Frontier has been employed by actors in the private sector to evaluate and understand the..

Advancements in biomarkers and momentum in precision medicine has paved the foundation for complex studies like basket..

Cytel and its collaborators have analyzed the challenges of conducting high-quality clinical research in LMICs – a..