The Cytel Blog: Perspectives on Enquiry & Evidence

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September 21, 2021

Three Underappreciated Benefits of Pareto for Empowered Trial Selection

Earlier this summer, we published a series of articles on the need to utilize weighting and prioritization tools in the..

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September 15, 2021

A Bayesian Optimal Design Advancing the Precision Medicine Approach

There is recognized heterogeneity within any given tumor‐type from patient to patient (inter‐patient heterogeneity),..

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September 14, 2021

Career Perspectives: Interview with Alyssa Biller, Senior Solutions Consultant

Alyssa Biller is a Senior Solutions Consultant at Cytel and currently plays a primary role in onboarding customers for..

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September 8, 2021

Progression Free Survival or Overall Survival? Reconciling an old debate with modern technology

A key decision in the design of clinical trials in oncology involves whether to select progression free survival (PFS)..

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August 31, 2021

CDISC Certification - is it worth taking?

For years, I have been telling the recruiters at Cytel to be wary of candidates claiming to have a CDISC Certification..

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August 20, 2021

Using Causal Inference for Decision Making

In clinical research, decision makers need to choose among different courses of action every day. Whether it is..

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August 18, 2021

What does it mean to reduce the risk of a faulty conclusion? A closer look at a new case study.

During the design of a clinical trial, many biotechs want to substantially reduce the risk of a good new therapy being..

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August 13, 2021

Finding the Optimal Trial Design Using Operations Research Methods

With the cloud computing power that we have today, we can run simulation of 1000s of designs with each design..

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August 10, 2021

CLRPerm: Cytel Scientists and Collaborators Propose a New Method for Meta-analysis for Rare Events

A few weeks ago I wrote about new research conducted by Cytel statisticians, on the challenge of conducting..

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The Cytel Blog: Perspectives on Enquiry & Evidence

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