March 5, 2021
Early stage Phase 2 clinical trials are often designed as multi-stage single arm trials, which quickly identify..
February 26, 2021
In the world of clinical trials, the pace of innovation is accelerating, and approaches such as Bayesian methods are..
February 18, 2021
In the last few years, there has been a growing interest in historical borrowing or augmented trials. There is an..
February 12, 2021
In recent times, Single arm trials are being increasingly used to assess new treatment interventions. They establish..
February 2, 2021
As the use of master protocols becomes more prevalent in drug development, Bayesian methods are extensively used to..
January 26, 2021
Bayesian models offer a flexible way of incorporating historical controls in the analysis of trial data (whether single..
December 21, 2020
2020 has been an unusually difficult year as the global pandemic impacted all of our lives. This year, the Cytel blog..
December 16, 2020
As we prepare to close the door on 2020, we asked Pantelis Vlachos, Principal/Strategic Consultant for Cytel, to share..
December 15, 2020
When designing clinical trials, biostatisticians and clinical development teams are often faced with a conundrum. Given..