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Earlier this month, my colleagues at Cytel Canada published a paper in JCO Clinical Cancer Informatics, offering a..

Former Commissioner of the FDA, Dr. Scott Gottlieb, in several public presentations, would bemoan missed chances to..

Early stage Phase 2 clinical trials are often designed as multi-stage single arm trials, which quickly identify..

Most people know that clinical drug discovery is usually conducted using either Frequentist or Bayesian methods. These..

In the world of clinical trials, the pace of innovation is accelerating, and approaches such as Bayesian methods are..

In the last few years, there has been a growing interest in historical borrowing or augmented trials. There is an..

In recent times, Single arm trials are being increasingly used to assess new treatment interventions. They establish..

As the use of master protocols becomes more prevalent in drug development, Bayesian methods are extensively used to..

Bayesian models offer a flexible way of incorporating historical controls in the analysis of trial data (whether single..