March 4, 2024
In this new installment of the Career Perspectives series, we had the privilege of interviewing Arnold van Aswegen,...
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June 9, 2023
In the ever-evolving landscape of clinical development, the need for robust evaluation of interim clinical data through...
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June 7, 2023
Since its founding in 1987, Cytel has been home to some of the most passionate, creative, and talented experts in the...
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January 25, 2023
People think in Bayesian terms all the time: we use prior information and the evidence at hand to make decisions in our...
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December 6, 2022
In this edition of the Career Perspectives series, I spoke with Veronica Chan, Principal Clinical Data Manager at...
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November 9, 2022
In this edition of the Career Perspectives series, I interview Malte Stein, Senior Biostatistician. Malte owned the...
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October 14, 2022
In this edition of the Career Perspectives series, I interview Nicolas Rouillé, Senior Director, Statistical...
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August 4, 2022
In this edition of the Career Perspectives series, I interview Allison Luccock, Director of Business Operations for...
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June 13, 2022
The International COVID-19 Data Alliance (ICODA) was formed to address the challenge of generating rapid and rigorous...
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May 24, 2022
Traditionally, clinical trials are expensive, long in duration, and have low success rate. But with the advent of rich...
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May 12, 2022
Synthetic control arm (SCA) methods are statistical methods that are seeing rapidly increasing use in comparative...
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May 5, 2022
While randomized control trials remain the industry gold-standard for regulatory and reimbursement submissions, there...
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May 4, 2022
If you are a pharmaceutical or biotech company seeking to enter the market with a new drug, you need to submit a...
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April 29, 2022
At ISPOR US 2022, Cytel’s HEOR & RWE experts will be contributing to a range of Issue Panels, In-person Podium...
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April 21, 2022
Sophisticated Bayesian Methods are gaining a lot of traction as they bring flexibility and speed to clinical trial...
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April 13, 2022
The Life Sciences landscape has seen an impactful digital evolution in the past two years. The pandemic has accelerated...
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April 12, 2022
In this edition of the Career Perspectives series, I interview Charles Warne, Associate Director of Biostatistics at...
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February 9, 2022
Data is the cornerstone of any clinical trial and is used to ultimately drive the decision-making process related to...
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January 26, 2022
In this edition of the Career Perspectives series, I interview Jessica Bhoyroo, Cytel Clinical Data Manager based in...
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January 20, 2022
Limited patient populations resulting in small study sample sizes is a difficulty associated with the development of...
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December 20, 2021
The promising zone design is an adaptive design which allows for sample size re-estimation based on the results of an...
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December 8, 2021
Despite the debate in the scientific community on adaptive sample size reassessment (SSR), noteworthy developments have...
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December 7, 2021
Sponsors bringing a successful new product to market have to overcome two hurdles: submission and reimbursement. For...
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November 30, 2021
The aim of any clinical research is to detect the actual difference in treatment effect between two groups (power) and...
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November 23, 2021
A randomized clinical trial (RCT) is the gold standard approach to demonstrate the efficacy and safety of novel...
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November 17, 2021
Traditionally, the teams responsible for clinical development and regulatory submissions do not consult the market...
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November 11, 2021
The value of Real World Evidence (RWE) is well known to many stakeholders, but its full potential for market access and...
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November 10, 2021
There are many reasons why traditional approaches to designing a clinical study are generally suboptimal and do not...
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November 4, 2021
The prominent European conference for Health Economics and Outcomes Research (HEOR), ISPOR Europe 2021, is around the...
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November 2, 2021
A good clinical study design performs well not only under the ideal target scenario. Statisticians should be able to...
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October 27, 2021
A staged investment strategy aligns R&D decisions and financial planning with the interim looks of a clinical trial. If...
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October 22, 2021
Currently, there are many treatment options for Cancer such as, Immunotherapy, Radiation Therapy, Chemotherapy etc. If...
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October 20, 2021
For health innovators, trial selection is a key success factor as there are no second chances. But how do you find the...
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October 6, 2021
Master Protocols are advanced and innovative clinical trial designs that can evaluate multiple therapies and disease...
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October 1, 2021
The COVID-19 pandemic elevated the challenge of designing and executing clinical trials within a substantially...
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September 24, 2021
We may be familiar with adaptive designs, but their complexity has made them difficult to implement and their benefits...
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September 14, 2021
Alyssa Biller is a Senior Solutions Consultant at Cytel and currently plays a primary role in onboarding customers for...
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August 20, 2021
In clinical research, decision makers need to choose among different courses of action every day. Whether it is...
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August 13, 2021
With the cloud computing power that we have today, we can run simulation of 1000s of designs with each design...
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August 5, 2021
It is important to compare competing interventions to determine value of medicines, both from clinical and societal...
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July 21, 2021
Conducting a transparent, targeted and robust benefit-risk assessment of a new drug or product is one of the most...
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July 20, 2021
Anil Golla is Vice President, Functional Service Provision (FSP) at Cytel. After 17 years of working at pharmaceutical...
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July 1, 2021
Synthetic control arms (SCAs) are best suited for situations when a single arm trial is run in a patient population...
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June 25, 2021
The main challenge associated with the development of therapies for rare diseases is typically the small study sample...
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June 24, 2021
Synthetic control arms (SCAs) leverage real world data from various sources or evaluations of historical clinical data...
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June 17, 2021
In Part 2 of this four-part blog series, we bust another myth surrounding synthetic control arms (SCAs) used in...
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June 14, 2021
ACDM’s (Association for Clinical Data Management) eDigital data management expert group (DMEG) focuses on driving...
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June 10, 2021
Over the past decade, single arm trials have emerged as an accepted way of assessing a new treatment intervention....
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June 4, 2021
Bayesian methods have been playing a key role in transforming clinical research in therapeutic areas such as oncology...
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June 3, 2021
Bayesian methods allow for the incorporation of prior knowledge, in terms of either expert opinion from clinicians or...
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May 7, 2021
When is a study design considered to be optimal? A good design performs well not only under the ideal target scenario...
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May 5, 2021
Cytel’s team of HEOR and Real-World Evidence (RWE) experts are all set to make a splash at the Virtual ISPOR on May 17...
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April 21, 2021
Two therapies are placed in head-to-head clinical trials when they are compared against each other as opposed to a...
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April 14, 2021
In the era of modern clinical development, several companies are turning towards novel and innovative approaches such...
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April 13, 2021
There has been an increasing use of digital measures in drug development recently. New wearables technologies can help...
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April 7, 2021
Scientists at Cytel recently published a paper in the Journal of the American Medical Association (JAMA). Among the...
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September 12, 2019
"If you went to bed last night as an industrial company, you're going to wake up today as a software and analytics...
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