The Cytel Blog: Perspectives on Enquiry & Evidence

Traditionally, clinical trials are expensive, long in duration, and have low success rate. But with the advent of rich..

For our first Winter Weekend Read, Cytel presents How to Use and Interpret the Results of a Platform Trial, a JAMA..

The aim of any clinical research is to detect the actual difference in treatment effect between two groups (power) and..

During the design of a clinical trial, many biotechs want to substantially reduce the risk of a good new therapy being..

“We found an optimal design in hours that might have taken months to find using standard methods,” reflected Fabien..

Earlier this year, Cytel founder Cyrus Mehta observed that clinical trial design is often treated like an art rather..

For decades, statisticians have cultivated methods to optimize and de-risk clinical trials for strong regulatory..

Suppose a statistician were to tell a clinical trial sponsor that it was possible to improve the power of the sponsor’s..

Clinical trial sponsors are more likely than ever to use the power of simulation and forecasting to evaluate the..