Perspectives on Enquiry & Evidence
Cytel's blog featuring the latest industry insights.
April 22, 2024
Written by Boaz N. Adler, Director, Global Product Engagement, and J. Kyle Wathen, Vice President, Scientific Strategy...
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April 5, 2024
Commercial and Open-Source Software Synergy for Clinical Trial Design
Written by Sydney Ringold, Customer Success Manager, and Kevin Trimm, Chief Product Officer In an ever-changing...
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March 13, 2024
Understanding Group Sequential Designs
Group sequential clinical trial designs — a type of adaptive clinical trial design — have emerged as a powerful tool in...
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February 20, 2024
Negative Binomial Distribution in Group Sequential Designs
In clinical trials based on count data, the aim is to compare independent treatment groups in terms of the rate of...
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February 2, 2024
The Living Model Approach for Systematic Literature Reviews
When building a disease model or an economic model, the assumption has been that updates to such models should only...
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January 26, 2024
Parameter Optimization of Multi-Arm Multi-Stage Designs
Innovations in the process of designing adaptive clinical trials have unlocked new possibilities for designing and...
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September 29, 2023
Innovative Clinical Trial Design: Commercial vs Open-Source Software? Why Not Both?
In the ever-changing field of clinical trial design, there is often a need to evaluate design options quickly and...
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August 22, 2023
Adaptive Multi-Arm Multi-Stage Designs: A Comparison of Methods
Written by Cyrus Mehta and Heather Struntz The significant time and cost, as well as high failure rates, of clinical...
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August 18, 2023
The Advantages of Forecasting Enrollment with a Model-Based Approach
The most common cause for incomplete Phase III trials is enrollment. Indeed, as many as 37% of trials miss...
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August 11, 2023
Demonstrating Value in Real Time with Living Models for Systematic Literature Reviews
Systematic literature reviews are essential for proving product value to health authorities, clinicians, and payers,...
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June 14, 2023
Embracing Innovation: Exploring the Design of Umbrella and Basket Trials
Medical research has come a long way in recent years, fueled by innovative trial designs that challenge traditional...
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