
Perspectives on Enquiry & Evidence
Cytel's blog featuring the latest industry insights.

November 20, 2023
Interpreting all guidelines before your first-in-human clinical trials can be overwhelming. While guidelines are...
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March 15, 2019
Strategic Applications of Pharmacometrics in Clinical Development
Quantitative pharmacology encompasses the many strategic advantages of using complex mathematical models to understand...
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January 30, 2019
Career Perspectives: Interview with Tina Checchio, Associate Director, Quantitative Pharmacology & Pharmacometrics
QPP remains at the heart of model based drug development. Short for Quantitative Pharmacology & Pharmacometrics, it...
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June 28, 2018
Non-Compartmental Analysis and the Early Phase Regulatory Environment
By Esha Senchaudhuri With thanks also to Jitendarreddy Seelam and Ramanatha Saralaya for their input. The fact of the...
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May 31, 2018
5 Reasons to Integrate MBMA Into Your Clinical Development Strategy
By Esha Senchaudhuri An important trend in clinical development involves integrating strategic pharmacometric analysis...
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August 10, 2017
4 Questions to Explore in Model-Informed Drug Development (Infographic)
Model-informed drug development has been defined by Richard Lalonde ( Lalonde, 2007) (1) as “Development and...
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June 12, 2017
Predictions of Pharmacodynamic Responses in Ulcerative Colitis Patient
The Population Approach Group in Europe (PAGE) represents a community with a shared interest in data analysis using the...
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January 5, 2017
SAS and NONMEM - a marriage made in heaven?
Nonlinear Mixed Effects Modeling (NONMEM) is a type of population pharmacokinetics/pharmacodynamics (popPK/PD) analysis...
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November 1, 2016
Pharmacometrics tools of the trade: 4 factors to consider
Unlike statistics which has been around in some form for hundreds of years, pharmacometrics is, by comparison, a...
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September 20, 2016
An efficient tool for model based meta-analysis
Drug development is an expensive and risky business. To maximize a compound’s ultimate chances of commercial as well as...
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September 13, 2016
Case Study:Exposure Response Modeling in Hematology
Exposure-response data gained from clinical studies can provide a basis for model-based analysis and simulation,...
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May 17, 2016
Scrambled Data – A Population PK/PD Programming Solution
Cytel participated at PharmaSUG 2016 in Denver recently. A key event on the statistical programming global calendar,...
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