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https://www.cytel.com/blog/recent-publication-gatekeeping-procedure-group-sequential
February 15, 2018
A recent publication in Biometrics ‘A Gatekeeping Procedure to Test a Primary and a Secondary Endpoint in a Group..
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https://www.cytel.com/blog/cvct-adaptive-workshop-blog
January 16, 2017
The Global Cardiovascular Clinical Trialists Forum is a key event bringing together leading experts from across the..
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https://www.cytel.com/blog/in-conversation-with-nejm-adaptive-designs
August 17, 2016
Following the recent publication of their review article Adaptive Designs for Clinical Trials in the New England..
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https://www.cytel.com/blog/adaptive-sample-size-re-estimation-efficiency
March 3, 2016
'The aim of a discussion should not be victory but progress.' This principle, expressed by the French essayist Joseph..
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https://www.cytel.com/blog/2-methods-for-evaluating-biomarker-subpopulations-in-adaptive-enrichment-time-to-event-trials
October 5, 2015
One consideration every sponsor of a biomarker-stratified confirmatory trial must take into account, is whether to..
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https://www.cytel.com/blog/adaptive-designs-for-confidence-intervals-the-latest-breed-of-adaptive-clinical-trials
September 17, 2015
Most people familiar with adaptive clinical trial designs are familiar with those statistical designs that reject the..
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https://www.cytel.com/blog/why-you-should-not-power-for-superiority-upfront-promising-zone-clinical-trials-with-adaptive-switch
June 26, 2015
Powering a trial for superiority can be financially risky. In some instances it may also prove unnecessary.
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https://www.cytel.com/blog/successful-adaptive-confirmatory-dose-response-pediatric-study
February 26, 2015
Cytel President and co-founder Cyrus Mehta has co-authored a paper on Infantile Hemangioma, recently published in the..
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https://www.cytel.com/blog/how-to-shorten-a-cardiovascular-outcome-trial-by-two-years
February 10, 2015
Cardiovascular outcome trials (CVOTs) have earned the reputation of being the untamable behemoths of the clinical..
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