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Cytel East®

As the character of the pharmaceutical industry changes, the need to create innovative clinical trials that de-risk uncertainty and optimize statistical design brings several advantages.
 
The rise in the number of such adaptations also increases the ability for statistical design to be tailored to the needs of a specific trial, thereby keeping patients safe and increasing the speed of new medicines to market. 
 
Used by statisticians worldwide for over 30 years, East® is the leading software tool for designing statistically optimized clinical trials. Designed by statisticians for statisticians, these are modules which deliver trusted results.

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About East®

East® provides users with a wide range of features, including sample size and power calculation tools, adaptive features planning, a trial monitoring dashboard, advanced simulations to test hypotheses before experimental implementation, and text-book-quality documentation and access to support from world-renowned statistical experts. 

Validated by the FDA, EMA, PMDA and other regulatory bodies, East® has been developed by clinical study design experts to produce studies which best address the critical questions confronted by clinical trial sponsors. 

Over 14 existing modules can be accessed to create early and late phase trials, multi-arm clinical trial designs, adaptive enrichment trials, and more. East® also provides intuitively organized tasks and workflows to further enhance productivity. 

Trusted and validated for over 30 years, East® has been used to design countless clinical studies performed in industry, government, and academia. By using East®, clinical trial designers can be confident they have the right design for their next clinical trial. 

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Power

Powerful simulation tools that allow comparison of promising clinical trial designs.

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Intelligence

East Users enjoy easy access to adaptive designs, group sequential designs, Bayesian methods and countless other leading innovative clinical trials.

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Confidence

Opportunities to refine superior clinical trial designs for scientifically rigorous studies using validated software.

Modules

BASE

Popular tools for fixed-sample clinical trials.

ENDPOINTS

Strategic testing of multiple endpoints

SEQUENTIAL

Tools for group sequential clinical trials with normal or binormal endpoints

SURVIVAL

Tools for group sequential clinical trials with survival endpoints

PREDICT

Predict future course of trial at outset and interim analysis

ESCALATE

Wide selection of model-based adaptive designs for Phase 1 dose escalation studies.

EXACT

Tools for small sample clinical trials with binomial endpoints.

MAMS

Multi-arm multi-stage clinical trials

SURVADAPT

Allow for sample size re-estimation in trials with survival endpoints

PROGRAM

Design through simulation

MCPmod

Multiple Comparison Procedure Modeling for Phase 2 dose-finding studies

MULTIARM

Tools for multi-arm fixed-sample clinical trials.

ADAPT

Allow for sample size re-estimation in trials with normal and binomial endpoints. 

ENRICH

Allow for population enrichment in trials with survival endpoints.

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