
Cytel East®
As the character of the pharmaceutical industry changes, the need to create innovative clinical trials that de-risk uncertainty and optimize statistical design brings several advantages.
About East®
East® provides users with a wide range of features, including sample size and power calculation tools, adaptive features planning, a trial monitoring dashboard, advanced simulations to test hypotheses before experimental implementation, and text-book-quality documentation and access to support from world-renowned statistical experts.
East® has been developed by clinical study design experts to produce studies which best address the critical questions confronted by clinical trial sponsors.
Over 14 existing modules can be accessed to create early and late phase trials, multi-arm clinical trial designs, adaptive enrichment trials, and more. East® also provides intuitively organized tasks and workflows to further enhance productivity.
Trusted and validated for over 30 years, East® has been used to design countless clinical studies performed in industry, government, and academia. By using East®, clinical trial designers can be confident they have the right design for their next clinical trial.


Intelligence
East Users enjoy easy access to adaptive designs, group sequential designs, Bayesian methods and countless other leading innovative clinical trials.

Confidence
Opportunities to refine superior clinical trial designs for scientifically rigorous studies using validated software.
Modules
BASE
Popular tools for fixed-sample clinical trials.
ENDPOINTS
Strategic testing of multiple endpoints
SEQUENTIAL
Tools for group sequential clinical trials with normal or binormal endpoints
SURVIVAL
PREDICT
Predict future course of trial at outset and interim analysis
ESCALATE
Wide selection of model-based adaptive designs for Phase 1 dose escalation studies.
EXACT
Tools for small sample clinical trials with binomial endpoints.
MAMS
Multi-arm multi-stage clinical trials
SURVADAPT
Allow for sample size re-estimation in trials with survival endpoints
PROGRAM
Design through simulation
MCPmod
Multiple Comparison Procedure Modeling for Phase 2 dose-finding studies
MULTIARM
Tools for multi-arm fixed-sample clinical trials.
ADAPT
Allow for sample size re-estimation in trials with normal and binomial endpoints.
ENRICH
Allow for population enrichment in trials with survival endpoints.