<img alt="" src="https://secure.lote1otto.com/219869.png" style="display:none;">
Skip to content

Advancing Innovative Clinical Trial Design

Platform trials, Master protocols and the challenges in execution
 

In recent years, master protocols have gained substantial support and provide an efficient way of testing compound(s) in a single and consistent framework. Master protocols expand on traditional trials by allowing new therapies, disease types, and/or disease subtypes to an on-going trial. Master protocols can be very flexible and improve the clinical development process, however, this flexibility increases the complexity and risk in trial execution.  

During this webinar Kyle Wathen will discuss: 

  • Platform studies and possible issues that may arise during the design phase and execution phase
  • Approaches to mitigate the risks and highlight strategies to help address these issues

Download Slides

 

Kyle Wathen

Kyle Wathen is currently Vice President, Scientific Strategy and Innovation at Cytel.   He has previous experience at Gilead Science, Janssen R&D, and M.D. Anderson Cancer Center and has developed a diverse background including industry, academia, statistical innovation, and software development.   He has more the 20 years of experience in design of innovative clinical trials such as platform trial, Bayesian approaches, and other adaptive approaches.  He has experience in many disease areas including oncology, neuroscience, infectious diseases, cardiovascular and inflammation.  He has also developed many simulation guided trial design packages and released several software packages including OCTOPUS, an R package for simulation of platform trials.  He is currently a co-chair of the DIA-ASA Master protocol workgroup, a member of the DIA – Bayesian Working Group and Vice Chair of the Biopharm Software Working Group. Kyle received his B.S. in Mathematics with a minor in computer science from University of Houston, M.S. in statistics from Texas A&M University and M.S. and Ph.D. in Biostatistics from the University of Texas: Graduate School of Biomedical Sciences.
 

Contact Us

Fill in the form below to get in touch