Conducting Sample Size Reassessment with Time-to-event Endpoints
This webinar provides an overview of the SURVIVAL and SURVADAPT modules. Dealing with time-to-event endpoints, this will enable you to increase your sample size when your results look promising but lack the targeted power.
At the end of the webinar you will be able to:
- Use simulation tools to illustrate complex survival data at the design stage
- Explore trade-offs between duration and patient accrual, choice of boundaries, spending functions and hazard functions
- Utilize the promising zone to determine increases in sample size given information acquired during the trial
Meet the Speaker
Pantelis Vlachos, Cytel
Before joining Cytel, Pantelis Vlachos was a Principal Biostatistician for Merck Serono in Geneva, and taught statistics at Carnegie Mellon University for 12 years. His research focus is adaptive designs, but mainly from a Bayesian perspective. Pantelis is a key contributor to the continuing development and training in the use of the East software package. Pantelis also has served on editorial boards of several scientific journals and online archives, including Managing Editor of “Bayesian Analysis” journal.