Are adaptive trials the answer? Would your next trial benefit from utilizing an innovative approach? Three ASCO posters co-authored by Cytel biostatistical experts and sponsors will showcase the growing adoption of population enrichment and sample-size re-estimation methods to improve oncology research. Visit booth #20101 to learn from with our adaptive design, specialized software and implementation experts.
PhUSE (Pharmaceutical Users Software Exchange) is staging their first Annual US Connect Conference in Raleigh, NC. Join our own statistical programmers participating in the 10 concurrent conference session streams. Meet our experts at the Cytel booth to better understand the benefits of centralizing your clinical trial biometrics functions.
The 2018 conference features a variety of plenary, parallel, breakout discussions
PCMG (Pharmaceutical Contract Management Group), is a dedicated and unique association of outsourcing professionals working in research and development functions within the pharmaceutical industry. The annual conference is taking place at The Grand Hotel Excelsior and the conference theme is "50 Shades of Outsourcing". Cytel is delighted to sponsor the event and Natalie Fforde, Senior Director of FSP Services at Cytel will be on hand over the three days to discuss any aspects of the conference and/or your outsourcing needs.
The 4th ISNPS (International Society of Non-Parametric Statistics) conference takes place in Salerno, Southern Italy and this year’s focus is recent advances and trends in several areas of nonparametric statistics, in order to facilitate the exchange of research ideas, collaboration amongst researchers from all over the world and further development of the field. This year, Cytel's Nitin Patel, Pralay Senchaudhuri and Jaydeep Bhattacharyya collaborate to present the session" "Comparing Saddle-point approximations and Exact methods in Logistic Regression". We hope you can join them for the plenary talks, roundtable discussions
Cytel is again a supporting sponsor of the Outsourcing Clinical Trials in the UK & Ireland annual conference. Join us in a debate towards developing the practical strategies to help your company, whether big or small, to improve developmental timelines.
Cytel statisticians will again play a prominent role at this year's American Statistical Association's Joint Statistical Meetings. Visit our booth #524 for a schedule of sessions showcasing our experts' own research, for demos of the latest version of East® and new software to support clinical trial decision-making.
Join us in the Pacific Northwest and network with your fellow biopharma and device development professionals to help move the Clinical Data Management discipline forward. Visit our booth to learn our CDM experts' contributions to the 2018 agenda.
Through in-depth research conducted with the regions' biopharma companies, this event will deliver insight, debate
This year in Frankfurt, PhUSE EU Connect is again Europe's largest congregation of biopharma statistical programmers. 2018 meeting themes include how our work can improve through insights into machine learning solutions, insight-enabling visualisations and interactive displays. Visit our booth to learn Cytel's own 2018 agenda contributions.
Cytel is again a supporting sponsor of the Outsourcing Clinical Trials conference in Boston. Join us there for a conversation towards developing the practical strategies to help your company, whether big or small, to improve developmental timelines.
Since 2011, the East Symposium and User Group Meeting
We are proud to announce our scientific committee includes Armin Schueler from host Merck KgA, Tobias Muetze of Novartis with Sanofi's Gautier Paux. The 2018 programme will be posted soon.
2018 Clinical Operations in Oncology Trials EU attendees can debate the practical strategies to help their company improve operational efficiencies in conducting oncology clinical research. Cytel adaptive trial and data science experts will again contribute. Learn about this year's presentation at our booth and how innovative approaches trial designs can increase your trial's chances for success.
Partnerships in Clinical Trials (PCT) Congress brings together trial stakeholders searching to improve clinical research. 2018 session streams include: "Disruptive Innovation, Technology and Big Dataset Access" and "How Small to Mid-Size Pharma and Biotech can Outsource to Find the Ideal Partner". Stop by the Cytel booth to learn how we're helping drug development sponsors to conduct better trials.
The 2018 Scrip Awards categories range from rewarding the broader achievements of drug development leaders to innovations in deal-making, advances in R&D and the more personal accomplishments of teams and individuals.
Cytel will again sponsor this important gathering of Life Science professionals and share how our Data Science experts are helping biopharma companies to formulate optimal program development strategies. In 2017, Cytel's Rajat Mukherjee spoke in the track "Transforming Big Data into Smart Data".
Cytel will have a considerable presence at the largest gathering of clinical study professionals in North America. Our own Charles Liu will speak on techniques and tools for building crucial "Go / No-Go" decision-making into the trial's interim analysis.
Stop by our booth to learn how a biometrics focus can improve your own program's chance of clinical success.
Archived Event Presentations
The 5th annual East User Group Meeting (EUGM) in Cambridge, MA, featuring expert contributions from hosts Biogen, AstraZeneca, Pfizer as well as Cytel. Their presentation topics included designing basket trials, new methods for optimizing the distribution of sites and utilizing safety statistics in adverse event monitoring.
See Cytel expert presentation
- Sample Size Re-Estimation: Controlling Type-1 Error, by Yannis Jemiai
- Bayesian Study Design to Leverage Informative Prior Information, by Jim Bolognese and Sam Hsiao
- Efficiency Promising of Zone Designs, by Cyrus Mehta, Sam Hsiao & Lingyun Liu
- PS4b Parallel Session, by Caroline Morgan
Hear Jim Bolognese and Narinder Nangia from Alkermes on designing Phase 2 trials based on program-level optimization (i.e., optimizing the entire Phase 2/3 drug development strategy). You'll learn how:
- Phase 2 sample size can be optimized to yield maximum eNPV when selecting 1 or 2 doses for Phase 3
- Studying more doses in Phase 2 can improve Probability of Success, yielding higher product eNPV, unless AE rates low for all doses
Download the slidesets and watch the presentation replays from the Cytel and Pfizer open seminar and applied trial design workshop focused on oncology and rare disease clinical development. In addition to biostatisticians, clinicians and R&D leadership as well will find the expert talks and trial design workshop enlightening.
East® Escalate version 6.4 adds two dose escalation design methods to support single- and dual-agent studies:
(1) BLRM method extension for dual-combination trials
- Simulate and compare designs under different dose-toxicity profile assumptions
- Determining best dose for next patient cohort based on modeling the accumulating data
- Communicating effectively with clinicians to guide dosing decisions, increase success rates
EUGM 2016 in London
In March 2016, biostatistical and drug development operations innovators met to help bridge the gap between newer methods and the medical, operational and regulatory realities.
Download expert slides
The Cytel and Sanofi trial design symposium presented ways to implement innovative approaches to dose finding and dose escalation trials, ultimately to better support confirmatory efforts. Hear expert presentations from trial and decision experts at AstraZeneca, Sanofi, Takeda and Cytel.