First Look at East® Version 6.5 and OK GO™ at Booth 524
July 29 - August 2
Cytel expert statisticians will be available to demo new software and to discuss adaptive trial design innovations: Arrange a demo
Stop by booth #524 to learn this year's program contributions from the Cytel team.
Join Cytel's Pantelis Vlachos and Charles Liu, your guides to applying three powerful statistical methodologies in the new East 6.5: 1. MCPMod, 2. Population Enrichment 3. Program-Level Design.
Cytel statisticians will again play a prominent role at this year's American Statistical Association's Joint Statistical Meetings. Visit booth #524 to learn about sessions featuring our experts' own research, and for demos of our new 2018 software: East® version 6.5 support Multiple Comparison Procedures, Adaptive Population Enrichment Designs and Program-Level Design tools.
JSM debut: OK GO® is our new software for “Go, No-Go” decisions in
Join us in the Pacific Northwest and network with your fellow biopharma and device development professionals to help move the Clinical Data Management discipline forward. Visit our booth #308 to learn our own CDM experts' contributions to the 2018 agenda.
Cytel sponsors this timely event designed for clinical research professionals in the German-speaking countries. Through in-depth research conducted with the regions' biopharma companies, this event will deliver insight, debate
This year in Frankfurt, PhUSE EU Connect is again Europe's largest congregation of biopharma statistical programmers. 2018 meeting themes include how our work can improve through insights into machine learning solutions, insight-enabling visualisations and interactive displays. Visit our booth to learn Cytel's own 2018 agenda contributions.
Cytel is again a supporting sponsor of the Outsourcing Clinical Trials conference in Boston. Join us there for a conversation towards developing the practical strategies to help your company, whether big or small, to improve developmental timelines.
Since 2011, the East Symposium and User Group Meeting
We're proud to announce our scientific committee includes Armin Schueler from host Merck KgA, Tobias Muetze of Novartis with Sanofi's Gautier Paux. The 2018 programme will be posted soon.
2018 Clinical Operations in Oncology Trials EU attendees can debate the practical strategies to help their company improve operational efficiencies in conducting oncology clinical research. Cytel adaptive trial and data science experts will again contribute. Learn about this year's presentation at our booth and how innovative approaches trial designs can increase your trial's chances for success.
Partnerships in Clinical Trials (PCT) Congress brings together trial stakeholders searching to improve clinical research. 2018 session streams include: "Disruptive Innovation, Technology and Big Dataset Access" and "How Small to Mid-Size Pharma and Biotech can Outsource to Find the Ideal Partner". Stop by the Cytel booth to learn how we're helping drug development sponsors to conduct better trials.
The 2018 Scrip Awards categories range from rewarding the broader achievements of drug development leaders to innovations in deal-making, advances in R&D and the more personal accomplishments of teams and individuals.
Cytel will again sponsor this important gathering of Life Science professionals and share how our Data Science experts are helping biopharma companies to formulate optimal program development strategies. In 2017, Cytel's Rajat Mukherjee spoke in the track "Transforming Big Data into Smart Data".
Cytel experts will reveal new tools and techniques at the largest gathering of clinical study professionals in North America. Our own Charles Liu will speak on the use of simulations to predict recruitment in "Accurate patient enrollment forecasting using Enforesys: Case studies and lessons learned".
Stop by our booth #207 to learn how a biometrics focus can improve your own program's chance of clinical success.
Archived Event Presentations
The 5th annual East User Group Meeting (EUGM) in Cambridge, MA, featuring expert contributions from hosts Biogen, AstraZeneca, Pfizer as well as Cytel. Their presentation topics included designing basket trials, new methods for optimizing the distribution of sites and utilizing safety statistics in adverse event monitoring.
See Cytel expert presentation
- Sample Size Re-Estimation: Controlling Type-1 Error, by Yannis Jemiai
- Bayesian Study Design to Leverage Informative Prior Information, by Jim Bolognese and Sam Hsiao
- Efficiency Promising of Zone Designs, by Cyrus Mehta, Sam Hsiao & Lingyun Liu
- PS4b Parallel Session, by Caroline Morgan
Hear Jim Bolognese and Narinder Nangia from Alkermes on designing Phase 2 trials based on program-level optimization (i.e., optimizing the entire Phase 2/3 drug development strategy). You'll learn how:
- Phase 2 sample size can be optimized to yield maximum eNPV when selecting 1 or 2 doses for Phase 3
- Studying more doses in Phase 2 can improve Probability of Success, yielding higher product eNPV, unless AE rates low for all doses
Download the slidesets and watch the presentation replays from the Cytel and Pfizer open seminar and applied trial design workshop focused on oncology and rare disease clinical development. In addition to biostatisticians, clinicians and R&D leadership as well will find the expert talks and trial design workshop enlightening.
East® Escalate version 6.4 adds two dose escalation design methods to support single- and dual-agent studies:
(1) BLRM method extension for dual-combination trials
- Simulate and compare designs under different dose-toxicity profile assumptions
- Determining best dose for next patient cohort based on modeling the accumulating data
- Communicating effectively with clinicians to guide dosing decisions, increase success rates
EUGM 2016 in London
In March 2016, biostatistical and drug development operations innovators met to help bridge the gap between newer methods and the medical, operational and regulatory realities.
Download expert slides
The Cytel and Sanofi trial design symposium presented ways to implement innovative approaches to dose finding and dose escalation trials, ultimately to better support confirmatory efforts. Hear expert presentations from trial and decision experts at AstraZeneca, Sanofi, Takeda and Cytel.
Solving Difficult Research Problems Using StatXact, hosted by Chris Corcoran