ASCPT 2018: Spotlight on Pharmacometrics
March 20 - 24
Cytel Director, Head Quantitative Pharmacology & Pharmacometrics and Phase 1 Statistics and 2018 Steering Committee Member Cecilia Fosser's joint session begins 7:00AM, March 22nd.
See the conference agenda
Visit the Cytel booth #517 to learn about our innovative quantitive pharmacology and pharmacometrics-related client work and open positions in the QPP field. On March 22nd, 7:00 AM, Cytel's own Cecilia Fosser serves as a member of the Pharmacometrics Steering Committee's Joint Session.
Adaptive Clinical Trials Symposium brings together senior-level executives from pharmaceutical and biotechnology companies to examine the best practices when taking advantage of adaptive design through case studies. We are looking forward to thought-provoking presentations, and the interactive panel discussions. Our own Seth Zuckerman, Senior Director Biostatistics will present recent adaptive trial design experiences, including how these designs are "real-world" performing. Seth joins an especially impressive speaking faculty of adaptive methods and implementation pioneers, along with more recent biopharma industry clinical trial innovators.
Save 15% off the standard registration rate with Discount Code: C1001CYTEL
Share drug development lessons learned over dinner and leave with some fresh perspectives. This session's industry speakers are Aoife Brennan, CMPO at
Adaptive trial designs can help address the challenges encountered in clinical development today by saving time, resources and improving the odds of success. Current FDA Commissioner Scott Gottlieb has championed adaptive trial designs as a promising approach in his 2017 confirmation testimony to the US Congress.
We're hosting a special event to look at "New Developments in Adaptive Designs" by our very own Cytel Co-Founder, Cyrus Mehta. Together with Pantelis Vlachos, Director Strategic Consulting they'll be presenting on “Early Phase Development". The team will be available after the presentations to answer questions. There will also be an opportunity for a hands-on session to review Cytel adaptive trial design software East® together with our new decision-inclusive OK GO software. Reserve your space today.
Webinar 11:00AM EDT
New regulatory expectations are taking shape, including the need for interactive and transparent clinical data handling, increased safety data demands
Register and gain a better understanding of the regulatory landscape and the practical steps available.
This conference will share best practice and lessons learned from implementing CDISC data standards and streamlining clinical research to enable connections to healthcare. This year, Cytel’s Angelo Tinazzi, who serves as part of the conference committee will chair one of the streams called “Challenges and Doing Better”. His participation also includes collaboration in the ADaM stream on “The Unveiled Secrets of ADaM”.
Visit the Cytel booth to learn more about our extensive experience working with CDISC standards and the planning and implementing of large migration projects for submissions.
The 2018 program is packed with interactive sessions and case studies providing attendees in this high stakes field with practical, implementable take-aways. Cytel's Natasa Rajicic will address these oncology development professionals seeking to streamline their trial operations while increasing the chances of program success.
Two Cytel clinical biometrics services and trial design projects are 2018 award nominees. Cytel and Biogen are finalists for "Clinical Partnership of the Year". Selected for "Most Innovative Clinical Trial Design" is the Dysphagia Detection System (DDS) from Nestlé Health Science with Cytel trial design. Join us in honoring the highest achievers in biopharma and device research.
There is something for every clinical statistical programmer at the annual PharmaSUG conference. A variety of compelling topics will be discussed along with hands-on training. Come to the Cytel booth #7 for daily prize drawings, plus the chance to meet our own statistical programmers. Ask about our open positions in the field, too.
Building on the success of the 2017 event, the American Statistical Association (ASA) Boston Chapter holds its second annual pharmaceutical symposium again at Takeda Pharmaceuticals. The full-day program features talks by regional trial design innovators including Harvard's L.J Wei, together with Cytel's own Charles Liu and
Cytel will again present an expert presentation at the annual forum for physicians in emerging biotech to exchange best practices in the advancement of drug development in Although the program is primarily designed for CMOs, other biotech and specialty R&D decision-makers and the investment stakeholders
This year's annual summit will feature more interactive formats aimed at enabling better collaboration between trial sponsors and solution providers and providing attendees with practical
Hosted by the University of Florida Department of Biostatistics, "From Data to Knowledge, Working for a Better World" is the theme for the 2018 IISA Annual meeting. Attend and hear Cytel's own President and Co-Founder, Cyrus Mehta deliver this year's keynote address.
Are adaptive trials the answer? Would your trial benefit from utilizing more innovative trial designs? Cytel ASCO posters collaborations with sponsor companies showcase the growing adoption of population enrichment and sample-size re-estimation methods to improve oncology research. Visit booth #20101 to engage with our adaptive design and implementation experts.
PhUSE (Pharmaceutical Users Software Exchange) is staging their first Annual US Connect Conference in Raleigh, NC. Join our own statistical programmers participating in the 10 concurrent conference session streams. Meet our experts at the Cytel booth to better understand the benefits of centralizing your clinical trial biometrics functions.
The 2018 conference features a variety of plenary, parallel, breakout discussions
PCMG (Pharmaceutical Contract Management Group), is a dedicated and unique association of outsourcing professionals working in research and development functions within the pharmaceutical industry. The annual conference is taking place at The Grand Hotel Excelsior and the conference theme is "50 Shades of Outsourcing". Cytel is delighted to sponsor the event and Natalie Fforde, Senior Director of FSP Services at Cytel will be on hand over the three days to discuss any aspects of the conference and/or your outsourcing needs.
The 4th ISNPS (International Society of Non-Parametric Statistics) conference takes place in Salerno, Southern Italy and this year’s focus is recent advances and trends in several areas of nonparametric statistics, in order to facilitate the exchange of research ideas, collaboration amongst researchers from all over the world and further development of the field. We're looking forward to the plenary talks,
Cytel is again a supporting sponsor of the Outsourcing Clinical Trials in the UK & Ireland annual conference. Join us in a debate towards developing the practical strategies to help your company, whether big or small, to improve developmental timelines.
Cytel statisticians will again play a prominent role at this year's American Statistical Association's Joint Statistical Meetings. Visit our booth #524 for a schedule of sessions showcasing our experts' own research, for demos of the latest version of East® and new software to support clinical trial decision-making.
Through in-depth research conducted with the regions' biopharma companies, this event will deliver insight, debate
Join us in the Pacific Northwest and network with your fellow biopharma and device development professionals to help move the Clinical Data Management discipline forward. Visit our booth to learn our CDM experts' contributions to the 2018 agenda.
This year in Frankfurt, PhUSE EU Connect is again Europe's largest congregation of biopharma statistical programmers. 2018 meeting themes include how our work can improve through insights into machine learning solutions, insight-enabling
2018 Clinical Operations in Oncology Trials EU attendees can debate the practical strategies to help their company improve operational efficiencies in conducting oncology clinical research. Cytel adaptive trial and data science experts will again contribute. Learn about this year's presentation at our booth and how innovative approaches trial designs can increase your trial's chances for success.
Cytel is again a supporting sponsor of the Outsourcing Clinical Trials conference in Boston. Join us there for a conversation towards developing the practical strategies to help your company, whether big or small, to improve developmental timelines.
The Scrip Awards categories range from rewarding the broader achievements of companies to innovations in deal-making, advances in R&D and the more personal accomplishments of teams and individuals.
Cytel will again sponsor this important gathering of Life Science professionals and share how our Data Science experts are helping biopharma companies to formulate optimal program development strategies. In 2017, Cytel's Rajat Mukherjee spoke in the track "Transforming Big Data into Smart Data".
Archived Event Presentations
The 5th annual East User Group Meeting (EUGM) in Cambridge, MA, featuring expert contributions from hosts Biogen, AstraZeneca, Pfizer as well as Cytel. Their presentation topics included designing basket trials, new methods for optimizing the distribution of sites and utilizing safety statistics in adverse event monitoring.
See Cytel expert presentation
- Sample Size Re-Estimation: Controlling Type-1 Error, by Yannis Jemiai
- Bayesian Study Design to Leverage Informative Prior Information, by Jim Bolognese and Sam Hsiao
- Efficiency Promising of Zone Designs, by Cyrus Mehta, Sam Hsiao & Lingyun Liu
- PS4b Parallel Session, by Caroline Morgan
Hear Jim Bolognese and Narinder Nangia from Alkermes on designing Phase 2 trials based on program-level optimization (i.e., optimizing the entire Phase 2/3 drug development strategy). You'll learn how:
- Phase 2 sample size can be optimized to yield maximum eNPV when selecting 1 or 2 doses for Phase 3
- Studying more doses in Phase 2 can improve Probability of Success, yielding higher product eNPV, unless AE rates low for all doses
Download the slidesets and watch the presentation replays from the Cytel and Pfizer open seminar and applied trial design workshop focused on oncology and rare disease clinical development. In addition to biostatisticians, clinicians and R&D leadership as well will find the expert talks and trial design workshop enlightening.
East® Escalate version 6.4 adds two dose escalation design methods to support single- and dual-agent studies:
(1) BLRM method extension for dual-combination trials
- Simulate and compare designs under different dose-toxicity profile assumptions
- Determining best dose for next patient cohort based on modeling the accumulating data
- Communicating effectively with clinicians to guide dosing decisions, increase success rates
EUGM 2016 in London
In March 2016, biostatistical and drug development operations innovators met to help bridge the gap between newer methods and the medical, operational and regulatory realities.
Download expert slides
The Cytel and Sanofi trial design symposium presented ways to implement innovative approaches to dose finding and dose escalation trials, ultimately to better support confirmatory efforts. Hear expert presentations from trial and decision experts at AstraZeneca, Sanofi, Takeda and Cytel.