Estimands: Not Just a Statistical Issue
In this webinar, Paul Terrill, Statistical Consultant, shares the bottom-line on estimands and discusses their implications for your trial's objectives, design, data collection, statistical analyses and conclusions. Paul also shares his guidance on managing the communication about estimands between multiple internal stakeholders, gaining internal buy-in, and ensuring that your trial’s objectives, design, conduct, analysis and interpretation are in line with the addendum.
Key Learning points
Estimands and their role in clinical trials - the essentials:
- The purpose of the addendum
- What is an estimand and why do they matter
- Which stakeholders need to understand them
- Why it is not just a statistical issue
How and why do estimands impact:
- The definition of a trial’s objectives
- The clinical data collected
-The statistical analyses
- The conclusions from the study
How to facilitate early discussions to harmonize trial objectives
The consequences of not thinking about estimands