Phase 1 Dose Escalation Trials with ESCALATE
This webinar will enable you to better characterize the maximum tolerated dose to improve your probability of success in later trials.
At the end of the webinar you will be able to:
- Simulate and analyse Phase 1 dose escalation trials for determining maximum tolerated dose (MTD)
- Understand a range of different methodologies that are used in Phase 1 dose escalation trials
- Communicate findings to the clinical team using East’s intuitive graphs and tables
- Simulate a dose escalation design followed by single-arm cohort expansion
Meet the Speaker
Pantelis Vlachos, Principal, Strategic Consulting, Cytel
Before joining Cytel, Pantelis Vlachos was a Principal Biostatistician for Merck Serono in Geneva, and taught statistics at Carnegie Mellon University for 12 years. His research focus is adaptive designs, but mainly from a Bayesian perspective. Pantelis is a key contributor to the continuing development and training in the use of the East software package. Pantelis also has served on editorial boards of several scientific journals and online archives, including Managing Editor of “Bayesian Analysis” journal.