We were fortunate to welcome Björn Bornkamp of Novartis to the EUGM 2016 presenting work he has developed jointly with Marius Thomas (1) on methods of adjusting treatment effect estimates in subgroup analyses with a focus on early phase trials.
The Cytel blog keeps you up to speed with the latest developments in biostatistics and clinical biometrics. Sign up for updates direct to your inbox. You can unsubscribe at any time.
Posts by Topic
- biostatistics (95)
- Adaptive Clinical Trials (82)
- Statistical Programming (54)
- Clinical Research Services (49)
- Clinical Development Strategy (47)
- adaptive designs (46)
- Oncology (40)
- Clinical Data (37)
- adaptive trials (33)
- Bayesian Methods (30)
- Data Management (30)
- Statistical Analysis (30)
- clinical trials (25)
- Cytel Strategic Consulting (24)
- Trial Design (23)
- CDISC (20)
- Cytel Consulting (20)
- Phase 3 (20)
- Early Phase Trials (19)
- East (19)
- Interim Analyses (19)
- Phase 1 (18)
- clinical research (18)
- phase 2 (18)
- Regulation (17)
- data manager (17)
- pharmacometrics (17)
- EAST 6.4 (15)
- EDC (15)
- SAS (15)
- SDTM (15)
- careers (15)
- clinical development (15)
- patient enrollment (15)
- Cyrus Mehta (14)
- Dose-Escalation (14)
- data science (14)
- Simulations (13)
- CRO (12)
- Dose-Finding (12)
- FDA (12)
- Program and Portfolio Optimization (12)
- Statistical Innovations in Clinical Development (12)
- database build (12)
- Cardiovascular (11)
- Promising Zone (11)
- pharmacology (11)
- Biometrics (10)
- Entrepreneurship (10)
- Recruitment (10)
- adaptive sample size re-estimation (10)
- Precision Medicine (9)
- big data (9)
- outsourcing (9)
- ADaM (8)
- Access to Slides PDF (8)
- Bayesian (8)
- CDM (8)
- East 6.3 (8)
- R programming (8)
- Trial Quality (8)
- clinical data management (8)
- go-no-go (8)
- sample size re-estimation (8)
- Case Study (7)
- Multi-Arm Multi-Stage Studies (7)
- Multi-Arm Studies (7)
- Software Simulations (7)
- enforesys (7)
- BLRM (6)
- DMC (6)
- East ESCALATE (6)
- East PREDICT (6)
- Enrichment (6)
- Nitin Patel (6)
- R language (6)
- Training and Education (6)
- feasibility studies (6)
- model-informed-drug-development (6)
- Biomarkers (5)
- Cytel Videos (5)
- MCP-Mod (5)
- Marvin Zelen (5)
- Phase I (5)
- R (5)
- Sample Size (5)
- ACES (4)
- Access to Paper PDF (4)
- CDASH (4)
- CRM (4)
- Exact Tests (4)
- Prediction (4)
- Predictive Enrichment (4)
- Rare Disease (4)
- Rstats (4)
- Safety (4)
- Seamless designs (4)
- Small Sample Sparse Data (4)
- StatXact (4)
- Trial Design Software (4)
- Trial Monitoring (4)
- forecasting (4)
- quantitative decision-making (4)
- randomization (4)
- real world evidence (4)
- Cytel Events (3)
- Dose Selection (3)
- Group Sequential (3)
- JSM (3)
- PK/PD (3)
- PSI Conference (3)
- PhUSE (3)
- Proof-of-Concept (3)
- R&D (3)
- Simulation & Biomarkers (3)
- Statistical Puzzles (3)
- White Paper (3)
- basket trials (3)
- custom software (3)
- exact statistics (3)
- genetic algorithm (3)
- optimization (3)
- p value (3)
- type 1 error (3)
- Adaptive Finance (2)
- Blind and Unblind Trials (2)
- Compass (2)
- Computing (2)
- EMA (2)
- Education (2)
- Efficacy (2)
- Lingyun Liu (2)
- Medical Devices (2)
- Monte Carlo (2)
- Movers & Shapers (2)
- NONMEM (2)
- PMDA (2)
- Pediatric (2)
- biomedical signals (2)
- estimands (2)
- machine learning (2)
- meta-analysis (2)
- patientricity (2)
- personalized medicine (2)
- pharmacovigilance (2)
- psychiatry and neuroscience (2)
- signal detection (2)
- trial planning (2)
- Adaptive Licensing (1)
- Antibiotic resistance (1)
- Biosimilars (1)
- Composite Endpoints (1)
- Cytel CliPLab (1)
- Cytel Congratulates (1)
- East Recruit (1)
- Eearly Development (1)
- Evidence Based Medicine (1)
- Exact Inference (1)
- Exact tests for categorical data (1)
- FMCG (1)
- Fourier (1)
- HTA (1)
- ISE (1)
- ISS (1)
- Infectious Diseases (1)
- NICE (1)
- PIPE (1)
- Predicted Interval Plots (1)
- RFP (1)
- Richard Branson (1)
- Risk Based Monitoring (1)
- Sam Hsaio (1)
- Scope conference (1)
- Statistics Article full PDF (1)
- Translational Medicine (1)
- Translational Statistics (1)
- Webinar Slides (1)
- What are... (1)
- benefit risk assessment (1)
- health economics (1)
- immunotherapy (1)
- infographic (1)
- medical ethics (1)
- medical writing (1)
- non parametric analysis (1)
- pattern recognition (1)
- permutations (1)
- population enrichment (1)
- signal processing (1)
- statistical communication (1)
- subgroup analysis (1)
- t-tests (1)
- time to event trials (1)
- time-to-even trials (1)
- treatment switch (1)
- webinar (1)