The Cytel Blog: Perspectives on Enquiry & Evidence

Recently we discussed examining clinical development through a Bayesian lens, in honor of Cytel co-founder Nitin Patel..

“We found an optimal design in hours that might have taken months to find using standard methods,” reflected Fabien..

Earlier this year, Cytel founder Cyrus Mehta observed that clinical trial design is often treated like an art rather..

For decades, statisticians have cultivated methods to optimize and de-risk clinical trials for strong regulatory..

Suppose a statistician were to tell a clinical trial sponsor that it was possible to improve the power of the sponsor’s..

When Cyrus Mehta introduced the Promising Zone Design over a decade ago, the new statistical method not only..

Much of the discussion about clinical trial design considers methods to optimize performance characteristics and..

ACDM’s (Association for Clinical Data Management) eDigital data management expert group (DMEG) focuses on driving..

When selecting clinical trial designs, how many design options should a sponsor explore? Would a sponsor feel more..