
Perspectives on Enquiry & Evidence
Cytel's blog featuring the latest industry insights.

September 15, 2021
There is recognized heterogeneity within any given tumor‐type from patient to patient (inter‐patient heterogeneity),...
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November 5, 2018
New publication addresses critical issues in ultra-orphan indications
Cytel biostatisticians Cyrus Mehta and Lingyun Liu, together with Charles Theuer, CEO of TRACON Pharmaceuticals have...
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January 23, 2018
Interview: Promoting precision medicine using data science
News Medical interviewed Dr. Rajat Mukherjee, Statistician, and Director of Data Science at Cytel to investigate the...
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September 27, 2016
Practical Challenges of the LUNG-MAP study
The Lung-MAP trial is an innovative biomarker driven 'precision medicine' study which evaluates five novel agents for...
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July 27, 2015
Evidence Based Medicine: 25 Years Later
We were saddened to learn earlier this year, of the passing of Professor David Sackett. Widely recognized as the father...
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April 9, 2015
Relative Clinical Efficiency and Phase 2 Biomarker Studies
Last year. Nature Reviews Drug Discovery asked the FDA’s Tatiana Prowell (Hematology & Oncology Products Division)...
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November 6, 2014
Translational Statistics: How to Move Beyond the Comfort Zone
Professor LJ Wei holds that rules are for lawyers, not (necessarily) clinicians. When designing modern clinical trials,...
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November 4, 2014
New Exploratory Trial Method Translates into Better Financial Strategy
A key stage of exploratory drug development is implementing a proof-of-concept study to demonstrate the safety of a...
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July 8, 2014
5 Reasons to Invest in Adaptive Designs for Population Enrichment
The above graphic is from Cyrus Mehta's slides on 'Adaptive Population Enrichment for Oncology Trials with Time to...
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June 26, 2014
Adaptive Designs for Precision Medicine: A Look at Pfizer
The rise of biomarker based treatments in oncology has meant a reconceptualization of what constitutes a particular...
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