
Perspectives on Enquiry & Evidence
Cytel's blog featuring the latest industry insights.

May 12, 2020
In our previous blog, “Remote Working Arrangement – How to get it right?”, we talked about how the need for social...
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August 31, 2016
An Introduction to BLRM
Traditional rule-based approaches to dose escalation such as 3+3 are widely used in early clinical development. They...
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October 28, 2014
Adaptive Dose Finding Using Toxicity Probability Intervals
Phase 1 oncology trials typically use either rule-based methods or model-based methods to determine the most acceptable...
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May 8, 2014
5 Reasons to Invest in Bayesian Dose-Escalation Methods
( Editor's note: This post has been refreshed in December 2016) Model based algorithms for Phase I dose-escalation have...
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