The Cytel Blog: Perspectives on Enquiry & Evidence

“We found an optimal design in hours that might have taken months to find using standard methods,” reflected Fabien..

Program and portfolio optimization creates a framework throughout the course of the clinical development journey, that..

Earlier this year, Cytel founder Cyrus Mehta observed that clinical trial design is often treated like an art rather..

For decades, statisticians have cultivated methods to optimize and de-risk clinical trials for strong regulatory..

Medical researchers and public health experts are becoming more reliant on meta-analyses to capture in summary form,..

Suppose a statistician were to tell a clinical trial sponsor that it was possible to improve the power of the sponsor’s..

When Cyrus Mehta introduced the Promising Zone Design over a decade ago, the new statistical method not only..

The main challenge associated with the development of therapies for rare diseases is typically the small study sample..

Much of the discussion about clinical trial design considers methods to optimize performance characteristics and..