Perspectives on Enquiry & Evidence

Cytel's blog featuring the latest industry insights.

Featured post

Innovative Clinical Trial Design: Commercial vs Open-Source Software? Why Not Both?

In the ever-changing field of clinical trial design, there is often a need to evaluate design options quickly and efficiently. But when it comes to evaluating options, which is better: commercial or open-source software? And does it need to be a question of either-or?

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Perspectives on Enquiry and Evidence

October 27, 2020

Bayesian Dose-Finding Designs – An Overview

Cytel recently conducted a webinar on Bayesian Dose-finding Designs for Modern Drug Development, presented by Dr. Yuan...

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September 2, 2016

Case Study: BLRM for Phase 1/2a Oncology Study

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August 31, 2016

An Introduction to BLRM

Traditional rule-based approaches to dose escalation such as 3+3 are widely used in early clinical development. They...

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April 22, 2016

Dual Agent Dose Escalation Designs

FDA draft guidance on “Co development of two or more unmarketed investigational drugs for use in combination” notes...

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November 19, 2015

A Competitive Alternative to Model-Based Dose-finding

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November 16, 2015

Takeda Pharmaceuticals' Ling Wang Talks Model-based Dose-finding Designs

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September 1, 2015

Modern Early Phase Clinical Trial Design Primer

If you’re in the practice of conducting early phase clinical trials, you’ve probably heard that modern trial designs...

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