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https://www.cytel.com/blog/how-and-why-to-implement-optimal-adaptive-promising-zone-designs
February 22, 2022
When determining the best possible statistical design for a particular trial, large pharmaceuticals and small biotechs..
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https://www.cytel.com/blog/parameter-estimation-approaches-in-adaptive-group-sequential-clinical-trials
December 20, 2021
The promising zone design is an adaptive design which allows for sample size re-estimation based on the results of an..
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https://www.cytel.com/blog/conditional-powers-vs-bayesian-predictive-power-for-adaptive-sample-size-reassessment
December 8, 2021
Despite the debate in the scientific community on adaptive sample size reassessment (SSR), noteworthy developments have..
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https://www.cytel.com/blog/improve-trial-design-with-group-sequential-designs-and-sample-size-re-estimation
October 1, 2020
Methods involving Group Sequential Designs is one of the earliest deviations from a traditional two-arm clinical trial..
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https://www.cytel.com/blog/cytel-co-founder-cyrus-mehta-presents-at-the-heart-failure-collaboratory
September 4, 2020
On Friday September 11, Cyrus Mehta, co-founder of Cytel, will be delivering a talk to the Heart Failure Collaboratory,..
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https://www.cytel.com/blog/webinar-replay-group-sequential-designs-and-sample-size-re-estimation-0
June 10, 2020
Cytel is conducting a webinar series that introduces biostatisticians to some of the more commonly used complex..
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https://www.cytel.com/blog/professor-jennison-on-group-sequential-designs-and-sample-size-re-estimation
May 27, 2020
In this blog, we speak with Christopher Jennison, Professor of Statistics at the University of Bath, UK. Professor..
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https://www.cytel.com/blog/publication-new-promise-promising-zone
February 8, 2019
A 2018 publication in the Biometrical Journal by Cytel’s Cyrus Mehta, Lingyun Liu and Sam Hsiao, ‘Optimal Promising..
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https://www.cytel.com/blog/new-publication-critical-issues-orphan-indications
November 5, 2018
Cytel biostatisticians Cyrus Mehta and Lingyun Liu, together with Charles Theuer, CEO of TRACON Pharmaceuticals have..
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