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https://www.cytel.com/blog/6-key-trials-for-understanding-adaptive-designs-for-confirmatory-clinical-trials
June 14, 2022
Suppose you had to choose six clinical trials intended for registration with regulatory agencies, only six, to explain..
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https://www.cytel.com/blog/together-trial-wins-the-sct-trial-of-the-year-award-interview-with-hinda-ruton
May 31, 2022
The TOGETHER Trial for COVID-19 therapies, designed by clinical trial specialists at Cytel won the Society for Clinical..
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https://www.cytel.com/blog/adaptive-designs-for-early-phase-development-are-we-asking-the-right-questions
May 3, 2022
In 2005, Pfizer launched a Phase 1 trial for the kinase inhibitor crizotinib. Six years later, it was approved, thanks..
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https://www.cytel.com/blog/dr.-julia-edwards-on-findings-from-published-trial-data-on-promising-zone-designs
November 30, 2021
The aim of any clinical research is to detect the actual difference in treatment effect between two groups (power) and..
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https://www.cytel.com/blog/seeing-uncertainty-new-frontiers-of-statistical-communication
March 9, 2021
When statistical sciences were in their infancy, the communicative benefits of statistics were widely touted. Thousands..
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https://www.cytel.com/blog/leveraging-synthetic-and-external-control-arms-using-bayesian-methods
February 12, 2021
In recent times, Single arm trials are being increasingly used to assess new treatment interventions. They establish..
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https://www.cytel.com/blog/simulation-based-clinical-trial-optimization
February 4, 2021
The past decade has witnessed the rise of simulations-based clinical trial optimization in a manner unimaginable to..
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https://www.cytel.com/blog/bayesian-methods-for-master-protocols
February 2, 2021
As the use of master protocols becomes more prevalent in drug development, Bayesian methods are extensively used to..
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https://www.cytel.com/blog/computation-and-clinical-trial-design-new-directions
January 29, 2021
Historically, advances in the statistical design of clinical trials have accompanied progress within the science and..
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