The Cytel Blog: Perspectives on Enquiry & Evidence

Suppose you had to choose six clinical trials intended for registration with regulatory agencies, only six, to explain..

The TOGETHER Trial for COVID-19 therapies, designed by clinical trial specialists at Cytel won the Society for Clinical..

In 2005, Pfizer launched a Phase 1 trial for the kinase inhibitor crizotinib. Six years later, it was approved, thanks..

The aim of any clinical research is to detect the actual difference in treatment effect between two groups (power) and..

When statistical sciences were in their infancy, the communicative benefits of statistics were widely touted. Thousands..

In recent times, Single arm trials are being increasingly used to assess new treatment interventions. They establish..

The past decade has witnessed the rise of simulations-based clinical trial optimization in a manner unimaginable to..

As the use of master protocols becomes more prevalent in drug development, Bayesian methods are extensively used to..

Historically, advances in the statistical design of clinical trials have accompanied progress within the science and..