February 14, 2023
The U.S. FDA has recently provided specific guidance[i] on the design and conduct of trials incorporating an external..
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February 9, 2023
Those familiar with simulation-guided design (SGD) know that it can be used for a wealth of clinical trial options:..
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February 8, 2023
Over the past years, probably the entire last decade, there have been several discussions on how to handle multiple..
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February 3, 2023
For clinical development and research and development teams, the Pareto Frontier can perform two functions. Let’s take..
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January 31, 2023
Asthma affects more than 235 million people worldwide, and due to lacking effective implementation of clinical..
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January 27, 2023
Should your clinical trial be adaptive? Trials that include a prospectively planned modification based on an interim..
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January 25, 2023
People think in Bayesian terms all the time: we use prior information and the evidence at hand to make decisions in our..
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January 23, 2023
Ever since the first immune checkpoint inhibitor was approved for market nearly twelve years ago, the industry has..
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January 20, 2023
A small biotech’s conventional carcinoma trial design was too expensive to implement and did not offer the opportunity..
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