February 14, 2023
The U.S. FDA has recently provided specific guidance[i] on the design and conduct of trials incorporating an external..
February 9, 2023
Those familiar with simulation-guided design (SGD) know that it can be used for a wealth of clinical trial options:..
February 8, 2023
Over the past years, probably the entire last decade, there have been several discussions on how to handle multiple..
February 3, 2023
For clinical development and research and development teams, the Pareto Frontier can perform two functions. Let’s take..
January 31, 2023
Asthma affects more than 235 million people worldwide, and due to lacking effective implementation of clinical..
January 27, 2023
Should your clinical trial be adaptive? Trials that include a prospectively planned modification based on an interim..
January 25, 2023
People think in Bayesian terms all the time: we use prior information and the evidence at hand to make decisions in our..
January 23, 2023
Ever since the first immune checkpoint inhibitor was approved for market nearly twelve years ago, the industry has..
January 20, 2023
A small biotech’s conventional carcinoma trial design was too expensive to implement and did not offer the opportunity..