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https://www.cytel.com/blog/optimal-promising-zone-designs-what-biotechs-need-to-know
November 15, 2021
Since its first publication ten years ago, Cyrus Mehta and Stuart Pocock’s Promising Zone Design for sample size..
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https://www.cytel.com/blog/keeping-the-promise-ten-year-anniversary-of-the-promising-zone-design
November 8, 2021
Ten years ago Cytel co-founder Professor Cyrus Mehta and Professor Stuart Pocock of the London School of Hygiene and..
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https://www.cytel.com/blog/measuring-non-adherence-and-non-persistence
October 21, 2021
A number of methods currently exist to measure non-adherence and non-persistence of medical therapies, for improved..
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https://www.cytel.com/blog/weighting-and-prioritization-for-trial-selection-new-webinar
October 14, 2021
When choosing the optimal clinical trial design for a given study, sponsors face critical questions like choice of..
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https://www.cytel.com/blog/non-adherence-and-non-persistence
October 7, 2021
‘Drugs do not work in patients who do not take them,’ said former surgeon general C. Everett Koop. Unfortunately, the..
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https://www.cytel.com/blog/three-underappreciated-benefits-of-pareto-for-empowered-trial-selection
September 21, 2021
Earlier this summer, we published a series of articles on the need to utilize weighting and prioritization tools in the..
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https://www.cytel.com/blog/progression-free-survival-or-overall-survival-reconciling-an-old-debate-with-modern-technology
September 8, 2021
A key decision in the design of clinical trials in oncology involves whether to select progression free survival (PFS)..
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https://www.cytel.com/blog/what-does-it-mean-to-reduce-the-risk-of-a-faulty-conclusion-a-closer-look-at-a-new-case-study
August 18, 2021
During the design of a clinical trial, many biotechs want to substantially reduce the risk of a good new therapy being..
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https://www.cytel.com/blog/clrperm-cytel-scientists-and-collaborators-propose-a-new-method-for-meta-analysis-for-rare-events
August 10, 2021
A few weeks ago I wrote about new research conducted by Cytel statisticians, on the challenge of conducting..
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