Cytel Board of Directors

Sarah W. Fuller

Co-Founder and President Emeritus,
Decision Resources Group

Sarah Fuller is Executive Chairman of Millennium Prevention Inc., which combines serious science with web-enabled platforms and apps that link consumers and providers to improve health and wellness outcomes. At its core, the company provides HIPAA-compliant personalized reports that help drive behavioral change. She is also President Emeritus of Decision Resources Inc., a leading research and advisory firm best known for its therapeutically-focused analyses of global pharmaceutical, biotechnology and medical device markets and for its research on the U.S. managed care industry. Previously, Ms. Fuller was a Vice President at Arthur D. Little, Inc., from which she led a buyout of Arthur D. Little Decision Resources in 1990.

At the University of Pennsylvania, she is a member of the Board of Trustees and ...of the Board of Overseers at the School of Arts and Sciences. In addition, she participates in the Huntsman and the Life Sciences and Management Advisory Boards.

Mrs. Fuller is Chairman and a Director of Cultural Survival, a non-profit organization that promotes the vision, rights and voice of indigenous people. She is also on the board The Forbes Consulting Group.

Ms. Fuller holds a B.A. from the University of Pennsylvania and an A.M. from Harvard University.

Per Lofberg

President of Caremark Pharmacy Services

Per Lofberg is Executive Vice President, CVS Caremark, and President of Caremark Pharmacy Services, the Pharmacy Benefits Manager and specialty pharmacy division of CVS Caremark, the largest pharmacy health care provider in the nation. He joined the company in January 2010 from Generation Health, an early stage company focused on genetic testing benefit management, where he served as President and CEO. He has a deep understanding and background in health care and is widely respected for his knowledge and understanding of the PBM business. As President, he has responsibility for all facets of the PBM business.

Prior to launching Generation Health, he was Co-Founder and CEO of Merck Capital Ventures, a venture capital company primarily funded by Merck to invest in emerging health care technologies. He also served as Chairman of Merck-Medco Managed Care LLC, which later became Medco Health Solutions. Before Merck-Medco, he was a Partner at The Boston Consulting Group and oversaw the firm’s worldwide health care practice.

Today, he serves on the boards of several private companies, including Decision Resources, PHT, Cytel and ImpactRx. He holds a Master of Science degree in Industrial Administration from Carnegie-Mellon University in Pittsburgh, Penn., and an undergraduate degree from Stockholm School of Economics in Sweden.

Cyrus Mehta

President and Founder, Cytel Inc.

An influential biostatistical thought leader, Cyrus Mehta has concentrated his research on developing innovative methods and software for flexible clinical trial designs and non-parametric exact statistics.

Dr. Mehta was a chief contributor to Cytel's development of permutational algorithms and their applications to categorical data analysis, nonparametric tests, power and sample size calculations, contingency tables analysis and, more generally to inference on the parameters in regression models for categorical data.

The same algorithms make it computationally feasible to obtain accurate p-values, confidence intervals and sample-size designs for small or unbalanced data sets and sparse contingency tables. These innovations have revolutionized general statistics practices.

His more recent research centers on adaptive and group sequential clinical trial methods and design tools. Dr. Mehta is the driving force behind Cytel's East®, the most widely used trial design and simulation software. He frequently provides adaptive trial design training for leading pharmaceutical companies, academic collaborators and FDA personnel.

Dr. Mehta has over 80 journal publications including JASA, Biometrics, Biometrika, Circulation, Statistics in Medicine and at ASCO. He and co-authors, Dr. Nitin Patel and Dr. Karim Hirji received the ASA's 1987 George W. Snedecor Award.

Dr. Mehta is an elected an American Statistical Association Fellow, named the Mosteller Statistician of the Year by the Massachusetts ASA Chapter, and an Elected Member of the International Statistical Institute. He remains an Adjunct Professor of Biostatistics at the Harvard School of Public Health and holds degrees from the Indian Institute of Technology and Massachusetts Institute of Technology.

Nitin Patel

Chairman and Chief Technology Officer
and Founder, Cytel Inc.

Nitin Patel is a widely respected expert in developing fast and accurate computer algorithms to implement computationally intensive statistical methods. At Cytel, Dr. Patel played a leading role in pioneering StatXact® and LogXact® the popular, award winning software for exact, nonparametric inference analysis.

Dr. Patel is primarily engaged now in researching and developing new clinical trial simulation and modeling tools for better decision-making at pharmaceuticals and device companies.

His Bayesian statistic dose-finding and computation methodology breakthroughs resulted in an FDA CRADA award to develop muchneeded software for adaptive trials. He also uses simulations to plan drug supply of complex trials, in randomization schemes, and predicting a program's Net Present Value and its ramifications on clinical strategy decision-making.

Dr. Patel has published in 70 refereed papers in statistics, operations research and computing, and co-authored a book on data mining for end-users. Along with co-authors Dr. Cyrus Mehta and Dr. Karim Hirji, he received the 1987 George W. Snedecor Award from the American Statistical Association. Dr. Patel is a Fellow of the American Statistical Association.

Dr. Patel has been Massachusetts Institute of Technology visiting professor since 1995. Previously he held a CMC chair professor at the Indian Institute of Management, and positions at Harvard, University of Michigan, University of Montreal and University of Pittsburgh. He won India's Vikram Sarabhai Medal for systems analysis research in 1985, served as President of the Operations Research Society, Vice President of the International Federation of Operational Research Societies and is a Fellow of the India Computer Society. Patel holds an Operations Research Ph.D. from the Massachusetts Institute of Technology.

P. Ranganath Nayak

Chief Executive Officer, Cytel Inc.

Ranganath Nayak is the Chief Executive Officer of Cytel. Earlier in his career, he was Vice President of The Boston Consulting Group, where he did extensive work in India, as well as working with US clients such as Gillette and Ford Motor Company. For two decades before that, he worked at Arthur D. Little, Inc., the technology and management consulting firm, where his consulting had a particular focus on innovation, new product development, and organizational learning. He also oversaw the Arthur D. Little School of Management.

Nayak is the co-author of Product Juggernauts: How Companies Mobilize to Generate a Stream of Market Winners, a Harvard Business School book on managing product development, and principal author of Breakthroughs!, a best selling study of hugely successful commercial innovations such as Tagamet, the microwave oven, Federal Express, the videocassette recorder, the Compact Disc, Post It notes, the CAT scanner, and the Toyota production system.

Dr. Nayak received a Ph.D. from the Massachusetts Institute of Technology.