Why SiZ for trials with multiple arms?

SiZ® modernizes formulating studies with more than one arm by combining design, simulation, visualization, and data analysis in one easily learned software. With customizable plots and graphs, SiZ clearly communicates even complex multiple arm concepts among program stakeholders.

• Design and analyze data using a choice parametric or p-value based multiple comparison procedures
• Weigh different design strategies with the fast simulation engine
• Simultaneously plot and contrast performance for several multiple comparison procedures
• Plot and compare Global power, Conjunctive power, Disjunctive power, and Family-Wise Error Rate (FWER)
• Assure careful control of type-1 error

Download SiZ® Multiple Comparisons Datasheet .pdf

Which comparison methods are available?

Multiple pairwise comparisons with a control

• Continuous endpoint: Difference of means
• Binary endpoint: Difference of proportions

Parametric multiple comparison procedures

• Dunnett’s single step
• Dunnett’s step down

P-value based multiple comparison procedures

• Bonferroni
• Sidak
• Weighted Bonferroni
• Holm’s step down
• Hochberg’s step up
• Hommel’s step up
• Fixed sequence
• Fallback

And SiZ® only costs $495?

Yes. The multi-arm capabilities are included in the base price. A SiZ® single annual license is $495 for commercial or academic/non-profit users. Contact us regarding multi-seat discounts.