On the Inefficiency of the Adaptive Design for Monitoring Clinical Trials (PDF)
Cyrus R. Mehta, Harvard University & Cytel Software; and
Anastasios A. Tsiatis, North Carolina State University
Presentation at the ASA-NJ's Spring Symposium, June 2002

Symposium on Group Sequential Inference (PDF)
Cyrus R. Mehta, Harvard University & Cytel Software
Presentation at the ASA-NJ's Spring Symposium, June 2002

Flexible Sample Size Considerations Using Information Based Interim Monitoring (PDF)
Cyrus R. Mehta, Harvard University & Cytel Software; and
Anastasios A. Tsiatis, North Carolina State University

Drug Information Journal, December 2001

Interim Monitoring of Group Sequential Trials Using Spending Functions for the Type I and Type II Error Probabilities (PDF)

Sandro Pampallona, ForMed, Statistics for Medicine;
Anastasios A. Tsiatis, North Carolina State University; and
Kyungmann Kim, University of Wisconsin

Drug Information Journal, December 2001