Cytel Reveals Latest Statistical Advancements to Support New Clinical Trial Designs at ASA/JSM 2006 

Cambridge, Massachusetts, USA - August 9, 2006 - From August 5th to 11th, Cytel thought leaders will present their latest biostatistical research, lead panel discussions, and instruct courses on adaptive clinical trial methodologies at the most prestigious forum of statistical science, the American Statistical Association’s 2006 Joint Statistical Meetings (JSM).

Over the last decade, Cytel leaders have profoundly influenced the evolution of modern clinical trials through software development for adaptive clinical trial designs driven by joint research with leading practitioners and academics, as well as through consulting on these designs. The resulting new methods are considered crucial to the biopharmaceutical industry’s effort to accelerate clinical drug development, while preserving patient safety and ethical standards.

Cytel Inc. co-founders Dr. Cyrus Mehta and Dr. Nitin Patel are both elected fellows of the American Statistical Association, and have published over 130 papers between them. Their latest effort, “Adaptive, Group Sequential and Decision Theoretic Approaches to Sample Size Determination”, will appear in the next edition of Statistics in Medicine journal.

Invited and contributing JSM presenters are Dr. Cyrus Mehta, Founder and President, Cytel Inc., Dr. Nitin Patel, Founder, Chairman, and Chief Technology Officer, Dr. Jerald Schindler, President of Cytel’s Pharmaceutical Research Division, and Dr. Pralay Senchaudhuri, VP of Research and Development.

Dr. Mehta will present: “ Confidence Intervals Following an Adaptive Group Sequential Design ”, and lead a technology workshop on “ East 4: Adaptive and Group Sequential Design, Interim Monitoring, & Simulation”.

Dr. Patel will present “ Comparison of Bayesian and Frequentist Adaptive Designs for Combination Proof-of-Concept/Dose Response Modeling Trials in Phase II”.

Dr. Schindler, will join Dr. Patel for “ Comparison of Bayesian and Frequentist Adaptive Designs...”, and will then participate in an “Adaptive Dose Response” panel discussion.

Dr. Senchaudhuri has co-authored the contributed paper “ Exact Inference for Contingency Tables with Correlated Data”.

Complete JSM presentation and conference info at: www.amstat.org/meetings/JSM/2006/

About Cytel
Cytel Inc. is a leading provider of clinical trial consulting services and specialized statistical software for the biopharmaceutical, medical device, academic, and government research markets. Cytel’s unique expertise in adaptive, flexible designs enables trial sponsors to improve drug development process efficiencies and trial success rates. Cytel’s East® system is widely used by biostatisticians and clinicians in industry, academia, and the FDA to design, monitor and simulate group sequential, and adaptive clinical trials.