Cytel's webcasts are free seminars that help to evaluate Cytel software products and clinical trial services. Our webcasts are typically 45 minutes long and followed by a Q&A session.

Register Now for this FREE ClinPhone® and Cytel Partnered Webinar

Optimizing Adaptive Trial Designs- Using Simulation Methodologies to Overcome Challenges

Click to choose either date/time – same presentation:
Tuesday, October 14, 2008 - 10:00 AM Eastern US
Thursday, October 16, 2008 - 1:00 PM Eastern US

Utilizing examples from actual trials, this webinar will explores how simulation tools help to determine the best design options and supply plans for adaptive trials. Nitin Patel, Cytel co-founder and CTO, is a guest speaker with ClinPhone's Graham Nicholls in this hour-long educational session.

Topics will include:

• Brief summary of adaptive trial designs and concepts
• Role of modelling tools to investigate study design properties
• Trial supply management considerations and options for reducing supply overage
• Evaluating supply requirements (both pre- and mid-study) via simulation.

An interactive Q&A session follows the presentations.

There is no charge for this informative WebEx webinar.

About the Presenters

Cytel's Nitin Patel is a recognized expert in the development of fast and  accurate computer algorithms to implement  computationally intensive statistical methods. At Cytel, he  plays a leading role in adaptive trial simulation methods  development utilzing both frequentist and Bayesian  statistics. Dr. Patel is a Fellow of the American Statistical  Association. He has published over sixty-five refereed  papers in statistics, operations research and computing  and a book on data mining. Dr. Patel has been a visiting professor at MIT since 1995. Previously, he was CMC chair professor at the Indian Institute of Management, Ahmedabad, and held positions at Harvard, and the Universities of Michigan, Montreal and of Pittsburgh. He won India's Vikram Sarabhai 1985 Medal for systems analysis research. Dr. Patel co-founded Cytel Software with Dr. Cyrus Mehta in 1987. He holds a Ph.D degree in Operations Research from MIT.   ClinPhone's Graham Nicholls is the Project Manager for ClinPhone's  Randomization and Trial Supply Management products and  services. Focused on the continued development of  advanced clinical trial technology solutions, Graham helps  guide the clinical technology strategies of some of the  world's biggest sponsor companies. Graham has  co-authored a number of publications on adaptive trial  designs, and is a regularly invited presenter at adaptive  trial innovation conferences. Graham Nicholls obtained an MSc degree in Biometry in 1995 and worked as a statistician in the pharmaceutical industry for over 10 years.  Graham co-authored a recent on adaptive trial designs publication, and has been invited to present at numerous meetings and conferences, recently including the 2008 DIA and the DIA Euro meetings.

Webinar Archives

• Making Bayesian Statistics Work in Your Clinical Trial
• Sneak Preview: What's New in East®
• Introducing StatXact - A comprehensive nonparametric inference package combining traditional asymptotic and advanced exact methods
• StatXact - Power and Sample Size Computations Using StatXact
• East - The Role of Futility Boundaries in Clinical Trials
• Designing Non-Inferiority Clinical Trials Using East
• Analyzing Categorical Data Using StatXact Version 6
• Designing Clinical Trials with Time-to-Event Endpoints
• Introducing StatXact Version 6 and Cytel Studio
• Flexible Efficacy and Futility Boundaries in East Version 3 (With a Discussion of Triangular Boundaries)
• Building Early Stopping for Futility into Clinical Trials with East Version 3
• Finding Accurate Results Using Exact Tests: The Utility of StatXact
• Designing Flexible Clinical Trials Using East Version 3